Dosimetric and clinical toxicity comparison of critical organ preservation with three-dimensional conformal radiotherapy intensity-modulated radiotherapy and RapidArc for the treatment of locally advanced cancer of the pancreatic head

摘要

PurposeWe compared dosimetry and clinical toxicity for 3-dimensional conformal radiotherapy (3D-crt), intensity-modulated radiotherapy (imrt), and RapidArc (Varian Medical Systems, Palo Alto, CA, U.S.A.) in locally advanced pancreatic cancer (lapcc). We hypothesized that the technique with better sparing of organs at risk (oars) and better target dose distributions could lead to decreased clinical toxicity.