Nucleotide Transition 390C-T in the Wilms Tumor 1 Gene: A Risk Factor of Hypospadias?

摘要

IntroductionThe gene Wilms' tumor 1 (WT1) encodes a unique transcription factor. Its defects are known to cause a wide range of complex genitourinary malformations and may contribute to non-syndromic forms of hypospadias.