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Data on the time of integration of the human mitochondrial pseudogenes (NUMTs) into the nuclear genome

机译:有关人类线粒体假基因(NUMT)整合入核基因组时间的数据

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摘要

The data and methods presented in this article are supplementing the research article "Integration of mtDNA pseudogenes into the nuclear genome coincides with speciation of the human genus. A hypothesis", DOI: 10.1016/j.mito.2016.12.001 (Gunbin et al., 2017) . Mitochondrial DNA is known to get inserted into nuclear DNA to form NUMTs, i.e. nuclear DNA pseudogenes of the mtDNA. We present here the sequences of selected NUMTs, in which time of integration can be determined with sufficient precision. We report their chromosomal positions , their position within the great ape mtDNA phylogeny, and their times of integration into the nuclear genome. The methods used to generate the data and to control their quality are also presented. The dataset is made publicly available to enable critical or extended analyzes.
机译:本文提供的数据和方法补充了研究文章``将mtDNA假基因整合到核基因组中与人类属的物种形成一致。一个假设'',DOI:10.1016 / j.mito.2016.12.001(Gunbin等。 ,2017)。已知线粒体DNA可以插入核DNA中形成NUMT,即mtDNA的核DNA假基因。我们在这里展示所选NUMT的序列,在其中可以以足够的精度确定积分时间。我们报告了它们的染色体位置,它们在大猿mtDNA系统发育中的位置以及它们整合入核基因组的时间。还介绍了用于生成数据和控制其质量的方法。公开提供数据集以进行关键或扩展分析。

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