Effect of Testosterone Replacement Therapy on Bone Mineral Density in Patients with Klinefelter Syndrome

摘要

PurposeKlinefelter syndrome (KS) is related to testicular insufficiency, which causes low testosterone levels in serum. Generally, sex hormone levels and bone mineral density (BMD) are lower in patients with KS than normal. We investigated the effects of testosterone replacement on serum testosterone levels and BMD in KS patients.