Hepatitis C virus clearance and less liver damage in patients with high cholesterol low-density lipoprotein cholesterol and APOE ε4 allele

摘要

BACKGROUNDCholesterol is related to improvements in the rate of sustained virological response and a robust immune response against the hepatitis C virus (HCV). APOE gene polymorphisms regulate cholesterol levels modifying the course of the HCV infection. The relationship between cholesterol, APOE alleles, and the outcome of HCV infection has not been evaluated in the admixed population of Mexico.