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Management of metal-on-metal hip implant patients: Who when and how to revise?

机译:金属对金属髋关节植入物患者的管理:谁何时以及如何修订?

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摘要

The debate on how best to manage patients with metal-on-metal (MOM) hip implants continues. With over 1 million patients affected worldwide, the impact is far reaching. The majority of the aggressive failures of MOM hip implants have been dealt with by revision hip surgery, leaving patients with a much more indolent pattern of failure of devices that have been in situ for more than 10 years. The longer-term outcome for such patients remains unknown, and much debate exists on how best to manage these patients. Regulatory guidance is available but remains open to interpretation due to the lack of current evidence and long-term studies. Metal ion thresholds for concern have been suggested at 7 ppb for hip resurfacing arthroplasty and below this level for large diameter total hip arthroplasties. Soft tissue changes including pseudotumours and muscle atrophy have been shown to progress, but this is not consistent. New advanced imaging techniques are helping to diagnose complications with metal hips and the reasons for failure, however these are not widely available. This has led to some centres to tackle difficult cases through multidisciplinary collaboration, for both surgical management decisions and also follow-up decisions. We summarise current evidence and consider who is at risk, when revision should be undertaken and how patients should be managed.
机译:关于如何最好地使用金属对金属(MOM)髋关节植入物治疗患者的争论仍在继续。全球有超过一百万的患者受到影响,其影响是深远的。 MOM髋关节植入物的大多数侵略性失败已通过翻修髋关节手术进行了处理,使患者在现场就位超过10年的装置出现了更加缓慢的失败模式。对于这类患者的长期结果仍然未知,并且关于如何最好地管理这些患者存在许多争论。监管指南是可用的,但由于缺乏当前证据和长期研究,因此仍有待解释。对于髋关节表面置换术,建议的金属离子阈值为7 ppb,对于大直径全髋关节置换术,建议低于此水平。包括假瘤和肌肉萎缩在内的软组织变化已显示出进展,但这并不一致。新的先进成像技术正在帮助诊断金属髋关节的并发症和失败的原因,但是这些方法尚未广泛应用。这导致一些中心通过多学科合作来解决疑难病例,包括外科手术管理决策和后续决策。我们总结了目前的证据,并考虑了谁有风险,何时应进行修订以及应如何治疗患者。

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