Yale School of Medicine produced the first proof-of-concept study on the viability of a “morning-after” pill for human use. This study was a result of a fruitful collaboration between a pair of Yale scientists, Drs. John M. Morris and Gertrude van Wagenen, who sought a non-abortion, post-coital contraceptive. They tested a variety of hormones, hormone-based synthetic drugs, and other compounds in monkeys in an effort to uncover a compound that was non-toxic but highly effective. Unfortunately, although they were unable to identify such a drug, their initial studies inspired other scientists to further pursue the concept of a “morning-after” pill, leading to the development of Food and Drug Administration (FDA)-approved emergency contraceptives.
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机译：耶鲁大学医学院就人类使用“事后”药片的可行性进行了首次概念验证研究。这项研究是耶鲁大学的两位科学家之间富有成果的合作的结果。约翰·莫里斯（John M. Morris）和格特鲁德·范·瓦格南（Gertrude van Wagenen），他们寻求一种不堕胎的性交后避孕药具。他们在猴子中测试了多种激素，基于激素的合成药物和其他化合物，以发现一种无毒但高效的化合物。不幸的是，尽管他们无法鉴定出这种药物，但他们的初步研究激发了其他科学家进一步追求“事后”药片的概念，从而导致了食品药品监督管理局（FDA）批准的紧急避孕药的发展。
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