首页> 美国卫生研究院文献>The World Allergy Organization Journal >Food Allergy Gastrointestinal Manifestations: 439 Probiotic Effect of the Regulation of Innate Immune Response dc and Adaptive Cellular Immune Response and the Balance TH1 TH2 TREG Through Sensors TLR-2 AND TLR-4 on the Intestinal Mucosa in BALB/C Health Status and Balb/C Status of Exposure to LPS
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Food Allergy Gastrointestinal Manifestations: 439 Probiotic Effect of the Regulation of Innate Immune Response dc and Adaptive Cellular Immune Response and the Balance TH1 TH2 TREG Through Sensors TLR-2 AND TLR-4 on the Intestinal Mucosa in BALB/C Health Status and Balb/C Status of Exposure to LPS

机译:食物过敏性胃肠道表现:439调节天然免疫反应直流和适应性细胞免疫反应以及通过传感器TLR-2和TLR-4平衡TH1TH2TREG对肠粘膜BALB / C健康状况的益生作用和暴露于LPS的Balb / C状态

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摘要

BackgroundThe concept of improving host defense as a preventive effort in the face of exposure to pathogens through the gut mucosal immune system must be developed where the normal intestinal flora plays an important role. Probiotics through various research can improve intestinal mucosal immune system, but so far the effect of probiotics on the regulation of innate immune responses of dendritic cells and adaptive cellular immune response as well as the balance of TH1, TH2, TREG through TLR-2 sensors and TLR-4 on intestinal mucosa Balb/c healthy status and Balb/c LPS exposure status is unclear. The purpose is to examine the effect of probiotics against dendritic cells regulation of innate immune responses and adaptive cellular immune response as well as the balance TH1, TH2, TREG through TLR-2 sensors and TLR-4, on the intestinal mucosa in Balb/c health status and Balb/c status of exposure to LPS.
机译:背景技术在正常肠道菌群起重要作用的地方,必须提出通过面对肠粘膜免疫系统来改善宿主防御能力以预防病原体的概念。益生菌通过各种研究可以改善肠道粘膜免疫系统,但到目前为止,益生菌对树突状细胞先天性免疫反应和适应性细胞免疫反应的调节作用以及通过TLR-2传感器和关于肠粘膜Balb / c健康状况和Balb / c LPS暴露状况的TLR-4尚不清楚。目的是检验益生菌对树突状细胞调节先天免疫应答和适应性细胞免疫应答以及通过TLR-2传感器和TLR-4平衡TH1,TH2,TREG对Balb / c肠粘膜的影响LPS暴露的健康状况和Balb / c状态。

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