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A Comparison of Culture Characteristics between Human Amniotic Mesenchymal Stem Cells and Dental Stem Cells

机译:人羊膜间充质干细胞与牙科干细胞之间培养特性的比较

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摘要

In the past decade, the field of stem cell biology is of major interest among researchers due to its broad therapeutic potential. Stem cells are a class of undifferentiated cells that are able to differentiate into specialised cell types. Stem cells can be classified into two main types: adult stem cells (adult tissues) and embryonic stem cells (embryos formed during the blastocyst phase of embryological development). This review will discuss two types of adult mesenchymal stem cells, dental stem cells and amniotic stem cells, with respect to their differentiation lineages, passage numbers and animal model studies. Amniotic stem cells have a greater number of differentiation lineages than dental stem cells. On the contrary, dental stem cells showed the highest number of passages compared to amniotic stem cells. For tissue regeneration based on animal studies, amniotic stem cells showed the shortest time to regenerate in comparison with dental stem cells.
机译:在过去的十年中,干细胞生物学领域因其广阔的治疗潜力而受到研究人员的广泛关注。干细胞是一类未分化的细胞,能够分化成专门的细胞类型。干细胞可分为两种主要类型:成体干细胞(成人组织)和胚胎干细胞(胚胎发育的胚泡阶段形成的胚胎)。这篇综述将讨论成年间充质干细胞的两种类型,即牙齿干细胞和羊膜干细胞的分化谱系,传代数和动物模型研究。羊水干细胞比牙干细胞具有更多的分化谱系。相反,与羊水干细胞相比,牙科干细胞显示出最高的传代次数。对于基于动物研究的组织再生,与牙科干细胞相比,羊膜干细胞的再生时间最短。

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