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Cardioembolic Sources in Stroke Patients in South of Brazil

机译:巴西南部中风患者的心脏栓塞来源

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摘要

Background. Stroke is a leading cause of mortality and disability in Brazil and around the world. Cardioembolism is responsible for nearly 30% of the origins of ischemic stroke. Methods. We analyzed data of 256 patients with cardioembolic ischemic stroke (according to TOAST classification) who were admitted into the Hospital São Lucas-PUCRS from October 2011 to January 2014. The cardioembolic subtype was divided into six subgroups: arrhythmias, valvular heart disease, coronary artery disease, cardiomyopathy, septal abnormalities, and intracardiac injuries. The prevalence of the most important cardiovascular risk factors and medications in use for prevention of systemic embolism by the time of hospital admission was analyzed in each patient. Results. Among 256 patients aged 60.2 +/− 6.9 years, 132 males, arrhythmias were the most common cause of cardioembolism corresponding to 50.7%, followed by valvular heart disease (17.5%) and coronary artery disease (16%). Hypertension (61.7%) and dyslipidemia (43.7%) were the most common risk factors. Less than 50% of patients with arrhythmias were using oral anticoagulants. Conclusions. Identifying the prevalence of cardioembolic stroke sources subgroups has become an increasingly important role since the introduction of new oral anticoagulants. In this study, arrhythmias (especially atrial fibrillation) were the main cause of cardioembolism.
机译:背景。中风是巴西乃至世界范围内导致死亡和残疾的主要原因。心脏栓塞占缺血性中风起源的近30%。方法。我们分析了2011年10月至2014年1月入院SãoLucas-PUCRS的256例心脏栓塞性缺血性中风(根据TOAST分类)的数据。心脏栓塞亚型分为六个亚组:心律失常,瓣膜性心脏病,冠状动脉疾病,心肌病,间隔异常和心内损伤。分析了每位患者入院时用于预防系统性栓塞的最重要的心血管危险因素和药物的患病率。结果。在256位年龄为60.2 +/- 6.9岁的患者中,有132位男性中,心律不齐是引起心脏栓塞的最常见原因,占50.7%,其次是瓣膜性心脏病(17.5%)和冠状动脉疾病(16%)。高血压(61.7%)和血脂异常(43.7%)是最常见的危险因素。少于50%的心律不齐患者使用口服抗凝药。结论。自从引入新的口服抗凝剂以来,确定心脏栓塞性中风来源亚组的流行已变得越来越重要。在这项研究中,心律不齐(尤其是房颤)是心脏栓塞的主要原因。

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