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The relationship between birth weight and congenital heart disease at Ahmed Gasim Cardiac Centre Bahri Sudan

机译:苏丹巴赫里艾哈迈德·加西姆心脏中心出生体重与先天性心脏病之间的关系

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摘要

Low birth weight is a known comorbidity of congenital heart disease (CHD). This study examines the relationship between CHD and birth weight of singletons, while attempting to remove factors that influence birth weight, and assesses the impact of CHD on growth in later life. The main objective is to study the relationship between birthweight and CHD. This is a cross-sectional study of 141 samples, covering all patients who were referred to the Paediatric Echocardiography Lab at Ahmed Gasim Cardiac Centre between September and October 2016. Infants with genetic syndromes or other major extracardiac abnormalities were excluded. The findings of this study clearly demonstrate that infants with CHD are more likely to be of low birth weight than the general Sudanese population, by a factor of 2.6. Of the sample, 31.9% were born with low or very low birthweight. The mean birth weight of the cases was 2.59 kg, which is 17.3% and 542.4 g less than the national average. CHD that cause a decrement in birth weight in a descending order of severity were atrial septal defect (−721 g/23%), patent ductus arteriosus (−669 g/21%), ventricular septal defect (−610 g/19%), pulmonary stenosis (−548 g/13%) and tetralogy of Fallot (248 g/8%). Pre/postnatal growth impairment is a common feature among children with CHD. No statistically significant relationship was found between the degree of birth weight/weight to age decrement and the specific type of hemodynamic disturbance. Our results are comparable to other studies that have been undertaken. However, Sudanese patients display larger birthweight deficits than other populations.
机译:低出生体重是已知的先天性心脏病(CHD)合并症。这项研究检查了冠心病与单身人士出生体重之间的关系,同时试图消除影响出生体重的因素,并评估了冠心病对晚年生长的影响。主要目的是研究出生体重和冠心病之间的关系。这是一项针对141个样本的横断面研究,涵盖了2016年9月至10月之间转诊至艾哈迈德·加西姆心脏中心儿科超声心动图实验室的所有患者。排除了患有遗传综合征或其他重大心外异常的婴儿。这项研究的结果清楚地表明,冠心病婴儿的出生体重比苏丹普通人群低,为2.6倍。在样本中,有31.9%的婴儿出生时体重过轻或过低。这些病例的平均出生体重为2.59千克,比全国平均水平低17.3%和542.4克。导致出生体重按严重程度递减的冠心病是房间隔缺损(-721 g / 23%),动脉导管未闭(-669 g / 21%),室间隔缺损(-610 g / 19%) ,肺动脉狭窄(-548 g / 13%)和法洛四联症(248 g / 8%)。冠心病患儿的出生前/产后生长障碍是其共同特征。在出生体重/体重对年龄的减少程度与特定的血流动力学障碍之间没有统计学上的显着关系。我们的结果与已经进行的其他研究相当。但是,苏丹患者的出生体重不足比其他人群更大。

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