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Predictors of In-Hospital Mortality for Stroke in Douala Cameroon

机译:喀麦隆杜阿拉的院内卒中死亡率预测指标

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摘要

Background. The objective of this study was to describe complications in hospitalized patients for stroke and to determine the predictive factors of intrahospital mortality from stroke at the Douala General Hospital (DGH) in Cameroon. Patients and Methods. A prospective cross-sectional study was carried out from January 1, 2010 to December 31, 2012, at the DGH. All the patients who were aged more than 15 years with established diagnosis of stroke were included. A univariate analysis was done to look for factors associated with the risk of death, whilst the predictive factors of death were determined in a multivariate analysis following Cox regression model. Results. Of the 325 patients included patients, 68.1% were males and the mean age was 58.66 ± 13.6 years. Ischaemic stroke accounted for 52% of the cases. Sepsis was the leading complications present in 99 (30.12%) cases. Independent predicting factors of in-hospital mortality were Glasgow Coma Scale lower than 8 (HR = 2.17 95% CI 4.86–36.8; P = 0.0001), hyperglycaemia at admission (HR = 3.61 95% CI 1.38–9.44; P = 0.009), and hemorrhagic stroke (HR = 5.65 95% CI 1.77–18; P = 0.003). Conclusion. The clinician should systematically diagnose and treat infectious states and hyperglycaemia in stroke.
机译:背景。这项研究的目的是描述喀麦隆杜阿拉综合医院(DGH)住院中风患者的并发症,并确定因中风住院的院内死亡率的预测因素。患者和方法。从2010年1月1日至2012年12月31日,在DGH进行了前瞻性横断面研究。所有年龄超过15岁且已确诊为中风的患者均包括在内。进行单因素分析以寻找与死亡风险相关的因素,而死亡的预测因素是在遵循Cox回归模型的多因素分析中确定的。结果。在325名患者中,男性占68.1%,平均年龄为58.66±13.6岁。缺血性中风占病例的52%。败血症是99例(30.12%)病例中的主要并发症。院内死亡率的独立预测因素是格拉斯哥昏迷评分低于8(HR = 2.17 95%CI 4.86–36.8; P = 0.0001),入院时高血糖(HR = 3.61 95%CI 1.38–9.44; P = 0.009),和出血性中风(HR = 5.65 95%CI 1.77-18; P = 0.003)。结论。临床医生应系统地诊断和治疗中风的感染状态和高血糖症。

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