Progesterone‐enhanced sperm hyperactivation through IP3–PKC and PKA signals

摘要

ProposeThe present study examined whether regulation of progesterone‐enhanced hyperactivation of spermatozoa is associated with the production of inositol 1,4,5‐trisphosphate (IP3) and diacylglycerol (DAG) by phospholipase C (PLC) and cyclic adenosine monophosphate (cAMP) by adenylate cyclase (AC), as well as activation of protein kinase C (PKC) and protein kinase A (PKA).