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Melatonin inhibits 17β-estradiol-induced migration invasion and epithelial-mesenchymal transition in normal and endometriotic endometrial epithelial cells

机译：褪黑素抑制17β-雌二醇诱导的正常和子宫内膜异位子宫内膜上皮细胞的迁移侵袭和上皮间质转化

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BackgroundMelatonin is a potential therapeutic agent for endometriosis, but its molecular mechanism is unclear. Here, we investigated the effect of melatonin on the epithelial-mesenchymal transition (EMT) in endometriotic endometrial epithelial cells and explored the pathway that might be involved.

机译：背景褪黑素是子宫内膜异位症的潜在治疗剂，但其分子机制尚不清楚。在这里，我们研究了褪黑激素对子宫内膜异位症子宫内膜上皮细胞上皮-间质转化（EMT）的影响，并探讨了可能涉及的途径。

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期刊名称 Reproductive Biology and Endocrinology : RBE
作者
Shasha Qi; Lei Yan; Zhao Liu; Yu-lan Mu; Mingjiang Li; Xingbo Zhao; Zi-Jiang Chen; Hui Zhang;
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作者单位

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年(卷),期 2018(16),-1
年度 2018
页码 62
总页数 12
原文格式 PDF
正文语种
中图分类生理学 ;
关键词
Endometrial epithelial cells Melatonin 17β-estradiol Migration and invasion Epithelial-mesenchymal transition;

机译：子宫内膜上皮细胞;褪黑激素;17β-雌二醇;迁移和侵袭;上皮-间质转化;

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专利

1. Melatonin inhibits 17β-estradiol-induced migration, invasion and epithelial-mesenchymal transition in normal and endometriotic endometrial epithelial cells [J] . Shasha Qi, Lei Yan, Zhao Liu, Reproductive Biology and Endocrinology . 2018 ,第1期

机译：褪黑素抑制17β-雌二醇诱导的正常和子宫内膜异位子宫内膜上皮细胞的迁移，侵袭和上皮间质转化
2. 3,6-dihydroxyflavone suppresses the epithelial-mesenchymal transition, migration and invasion in endometrial stromal cells by inhibiting the Notch signaling pathway [J] . M.-M. Yu, Q.-M. Zhou European review for medical and pharmacological sciences. . 2018 ,第12期

机译：3,6-二羟基黄酮通过抑制Notch信号通路抑制子宫内膜间质细胞的上皮-间质转化，迁移和侵袭
3. Normal endometrial stromal cells regulate 17-estradiol-induced epithelial-mesenchymal transition via slug and E-cadherin in endometrial adenocarcinoma cells in vitro [J] . Zhang Hui, Li Hongyan, Qi Shasha, Gynecological endocrinology: the official journal of the International Society of Gynecological Endocrinology . 2017 ,第1a6期

机译：正常子宫内膜基质细胞通过体外通过子宫内膜腺癌细胞中的粘土和E-钙粘蛋白调节17-雌二醇诱导的上皮 - 间充质转变
4. PLK1 Promotes Invasion of Esophageal Squamous Cell Carcinoma Cells through Inducing Epithelial-mesenchymal Transition [C] . Jiyu Ju, Wenjing Yu, Chunling Zhao International Conference on Applied Sciences, Engineering and Technology . 2014

机译：PLK1通过诱导上皮 - 间充质转换来促进食管鳞状细胞癌细胞的侵袭
5. Extracellular vesicle-encapsulated miR-30e suppresses　cholangiocarcinoma cell invasion and migration via inhibiting epithelial-mesenchymal transition [D] . 太田, 雄 2019

机译：细胞外囊泡包裹的miR-30e通过抑制上皮-间质转化抑制胆管癌细胞的侵袭和迁移
6. Shikonin inhibits migration and invasion of triple-negative breast cancer cells by suppressing epithelial-mesenchymal transition via miR-17-5p/PTEN/Akt pathway [O] . Chang Bao, Tao Liu, Lingbo Qian, 2021

机译：Shikonin通过MiR-17-5P / PTEN / PTEN / AKT途径抑制上皮 - 间充质转换来抑制三阴性乳腺癌细胞的迁移和侵袭
7. Shikonin inhibits migration and invasion of triple-negative breast cancer cells by suppressing epithelial-mesenchymal transition via miR-17-5p/PTEN/Akt pathway [O] . Chang Bao, Tao Liu, Lingbo Qian, 2020

机译：Shikonin通过MiR-17-5P / PTEN / PTEN / AKT途径抑制上皮 - 间充质转换来抑制三阴性乳腺癌细胞的迁移和侵袭

Melatonin inhibits 17β-estradiol-induced migration invasion and epithelial-mesenchymal transition in normal and endometriotic endometrial epithelial cells

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