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Time-dependent mRNA expression of selected pro-inflammatory factors in the endometrium of primiparous cows postpartum

机译:产后初产母牛子宫内膜中某些促炎因子的时间依赖性mRNA表达

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摘要

BackgroundInflammatory processes and infections of the uterine wall must be accepted as a physiological event in dairy cows after calving. This might result in clinical or subclinical endometritis which is assumed to impair reproductive performance in the current lactation. Several cytokines and acute phase proteins have been discussed as local and systemic mediators of these inflammatory processes. The aim of the present study was to investigate the endometrial mRNA expression of the chemokine CXC ligand 5 (CXCL5), interleukin 1β (IL1B), IL6, IL8, tumour necrosis factor alpha (TNF), prostaglandin-endoperoxide synthase 2 (PTGS2) and haptoglobin (HP) in the postpartum period.
机译:背景产犊后,炎症过程和子宫壁感染必须作为奶牛的生理事件来接受。这可能会导致临床或亚临床子宫内膜炎,这被认为会损害当前泌乳的生殖能力。已经讨论了几种细胞因子和急性期蛋白作为这些炎症过程的局部和全身性介质。本研究的目的是研究趋化因子CXC配体5(CXCL5),白介素1β(IL1B),IL6,IL8,肿瘤坏死因子α(TNF),前列腺素-过氧化物合成酶2(PTGS2)的子宫内膜mRNA表达。产后触珠蛋白(HP)。

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