An individual urinary proteome analysis in normal human beings to define the minimal sample number to represent the normal urinary proteome

摘要

BackgroundThe urinary proteome has been widely used for biomarker discovery. A urinary proteome database from normal humans can provide a background for discovery proteomics and candidate proteins/peptides for targeted proteomics. Therefore, it is necessary to define the minimum number of individuals required for sampling to represent the normal urinary proteome.