首页> 美国卫生研究院文献>Proceedings of the National Academy of Sciences of the United States of America >A multisubunit complex containing the SWI1/ADR6SWI2/SNF2 SWI3 SNF5 and SNF6 gene products isolated fromyeast.
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A multisubunit complex containing the SWI1/ADR6SWI2/SNF2 SWI3 SNF5 and SNF6 gene products isolated fromyeast.

机译:包含SWI1 / ADR6的多亚基复合体SWI2 / SNF2SWI3SNF5和SNF6基因产物分离自酵母。

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摘要

A complex containing the products of the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 genes and four additional polypeptides has been purified from extracts of the yeast Saccharomyces cerevisiae. Physical association of these proteins was demonstrated by copurification and coimmunoprecipitation. A potent DNA-dependent ATPase copurified with the complex, and this activity was evidently associated with SWI2/SNF2.
机译:已从酵母酿酒酵母提取物中纯化出含有SWI1 / ADR6,SWI2 / SNF2,SWI3,SNF5和SNF6基因产物和四种其他多肽的复合物。这些蛋白质的物理缔合通过共纯化和共免疫沉淀来证明。一个有效的DNA依赖的ATPase与复合物共纯化,并且这种活性显然与SWI2 / SNF2有关。

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