Repair of surgical bone defects grafted with hydroxylapatite + β-TCP combined with hyaluronic acid and collagen membrane in rabbits: A histological study

摘要

ObjectivesThis study aimed to assess the repair of bone defects with or without grafts using biphasic synthetic micro-granular hyaluronic acid (HA) with β-TCP and bovine type I collagen (Osteon II Collagen) with or without either hyaluronic acid or a collagen membrane in surgically created bone defects in the tibia of rabbits.