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Acetonitrile ingestion: delayed onset of cyanide poisoning due to concurrent ingestion of acetone.

机译:摄入乙腈:由于同时摄入丙酮导致氰化物中毒的发作延迟。

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摘要

A fatal case of acetonitrile ingestion is reported. The patient presented having apparently taken an overdose but was well until around 24 hours after the supposed ingestion, when cardiovascular collapse and profound metabolic acidosis developed. Later investigation revealed that the patient had taken acetone and acetonitrile. Acetone is known to slow the metabolism of acetonitrile to cyanide, thereby delaying the appearance of toxicity.
机译:据报道致命的乙腈摄入。患者出现明显服药过量,但直到假定摄入后约24小时才恢复健康,当时心血管衰竭和严重的代谢性酸中毒发生。后来的调查显示该患者服用了丙酮和乙腈。已知丙酮会减慢乙腈向氰化物的代谢,从而延迟毒性的出现。

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