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Rare Elizabethkingia anophelis meningitis case in a Danish male

机译:丹麦男性罕见的伊丽莎白女王基氏按蚊脑膜炎

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摘要

Introduction. Elizabethkingia anophelis is a Gram-negative, aerobic, non-motile rod belonging to the family Flavobacteriaceae. Over the last 5 years, it has emerged as an opportunistic human pathogen involved in neonatal meningitis and sepsis, as well as nosocomial outbreaks. It has been isolated from the midgut of the Anopheles gambiae mosquito, but there is no evidence for a role of the mosquito in human infections, and very little is known regarding the routes of transmission to humans. Recent studies, primarily from South-East Asia, suggest that E. anophelis, and not Elizabethkingia meningoseptica, is the predominant human pathogen of this genus. However, identification to the species level has been difficult due to the limitations of the current MALDI-TOF MS (matrix-associated laser desorption ionization-time of flight MS) systems for correct species identification.
机译:介绍。 Elizabethkingia anophelis是革兰氏阴性,有氧,不运动的杆,属于黄杆菌科。在过去的五年中,它已成为机会性人类病原体,涉及新生儿脑膜炎和败血症以及医院内暴发。它已从冈比亚按蚊的中肠中分离出来,但没有证据表明该蚊子在人类感染中起作用,而且关于向人类​​传播的途径知之甚少。最近的研究(主要来自东南亚)表明,按蚊大肠杆菌(E. anophelis)是该属的主要人类病原体,而不是脑膜炎伊丽莎白氏菌。但是,由于用于正确物种识别的当前MALDI-TOF MS(与基质相关的激光解吸电离飞行时间MS)系统的局限性,很难在物种水平上进行识别。

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