Polycystic ovary syndrome androgen excess and the risk of nonalcoholic fatty liver disease in women: A longitudinal study based on a United Kingdom primary care database

摘要

BackgroundAndrogen excess is a defining feature of polycystic ovary syndrome (PCOS), which affects 10% of women and represents a lifelong metabolic disorder, with increased risk of type 2 diabetes, hypertension, and cardiovascular events. Previous studies have suggested an increased risk of nonalcoholic fatty liver disease (NAFLD) in individuals with PCOS and implicated androgen excess as a potential driver.