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Cognitive Function Characteristics of Parkinsons Disease with Sleep Disorders

机译:帕金森病伴睡眠障碍的认知功能特征

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摘要

Objective. The aim of this study was to investigate the cognitive function characteristics of Parkinson's disease (PD) with sleep disorders. Methods. Consecutive patients with PD (n = 96), patients with primary sleep disorders (n = 76), and healthy control subjects (n = 66) were assessed. The patients with PD were classified into sleep disorder (PD-SD) and non-sleep disorder (PD-NSD) groups. Results. Among 96 patients with PD, 69 were diagnosed with a sleep disorder. There were 38 sleep disorder cases, 31 RBD cases, and 27 NSD cases. On the Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), and MoCA subtests, patients in the PD-SD, primary sleep disorder, and PD-NSD groups exhibited lower scores than those in the control group. Moreover, the PD-SD patients exhibited more significant cognitive impairment than was observed in the primary sleep disorder patients. In the PD-SD subgroup, the attention scores on the MoCA and on MoCA subtests were lower in the PD with RBD group than in the PD with insomnia group. Conclusion. PD with sleep disorders may exacerbate cognitive dysfunction in patients. PD associated with different types of sleep disorders differentially affects cognitive functions, and patients with PD with RBD exhibited poorer cognitive function than was seen in patients with PD with insomnia.
机译:目的。这项研究的目的是调查帕金森病(PD)睡眠障碍的认知功能特征。方法。对连续的PD患者(n = 96),原发性睡眠障碍患者(n = 76)和健康对照组(n = 66)进行了评估。 PD患者分为睡眠障碍(PD-SD)和非睡眠障碍(PD-NSD)组。结果。在96名PD患者中,有69名被诊断患有睡眠障碍。睡眠障碍病例38例,RBD病例31例,NSD病例27例。在小精神状态检查(MMSE),蒙特利尔认知评估(MoCA)和MoCA子测验中,PD-SD,原发性睡眠障碍和PD-NSD组的患者得分均低于对照组。此外,与原发性睡眠障碍患者相比,PD-SD患者表现出更大的认知障碍。在PD-SD子组中,RBD组PD的MoCA和MoCA子测试的注意力得分低于失眠组PD。结论。患有睡眠障碍的PD可能会加重患者的认知功能障碍。与不同类型的睡眠障碍相关的PD对认知功能的影响不同,患有RBD的PD患者的认知功能比失眠的PD患者差。

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