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Intérêt de la TEP-TDM dans le cancer broncho-pulmonaire primitif non à petite cellule

机译:PET-CT对原发性非小细胞支气管肺癌的兴趣

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摘要

Bronchopulmonary cancer is a real public health problem. Morphological imaging plays a central role in its diagnosis, staging as well as post-therapeutic assessment but it has some limitations. Metabolic imaging is a more recent technique which allows to significantly improve the overall imagery performance. We conducted a retrospective, descriptive and analytical study at the Ibn Sina Hospital and at the Military Hospital of instruction Mohammed V in Rabat over a period of 18 months, between September 2014 and February 2016, in order to evaluate the role of Fluorodeoxyglucose-PET/CT in the staging and restaging of non-small cell bronchopulmonary cancer. Initial staging showed a vast majority of locally advanced and metastatic stages: stage IV (40%), Stage IIIB (36%), Stage IIIA (16%), Stage II (8%). PET-CT allowed to detect new sites which were not initially seen on CT scan in 24 cases: 15 new ganglion sites, 8 new adrenal sites and 6 sites of bone lesions. PET/CT allowed to modify initial tumor stage in 60% of cases: upstaging in 23 patients (46%) and downstaging in 7 patients(14%). The initial stage remained unchanged in 40% of patients. Our study confirms the data from the literature concerning the superiority of PET-CT in comparison with CT scan, but only in the optimization of the non-small cell bronchopulmonary cancer management, in particular in locoregional and distant staging.
机译:支气管肺癌是一个真正的公共卫生问题。形态学成像在其诊断,分期以及治疗后评估中起着核心作用,但它有一些局限性。代谢成像是一种更新的技术,可以显着提高整体成像性能。我们在2014年9月至2016年2月的18个月内,对拉本特的伊本·西那医院和穆罕默德五世军事医院进行了回顾性,描述性和分析性研究,以评估氟脱氧葡萄糖-PET / CT在非小细胞支气管肺癌分期和再分期中的作用。初始分期显示了绝大多数局部晚期和转移性阶段:IV期(40%),IIIB期(36%),IIIA期(16%),II期(8%)。 PET-CT可检测出24例最初在CT扫描中未发现的新部位:15个新神经节部位,8个新肾上腺部位和6个骨病变部位。 PET / CT可改变60%的患者的初始肿瘤分期:23例患者(46%)上调,7例患者(14%)上调。 40%的患者的初始阶段保持不变。我们的研究证实了文献中有关PET-CT与CT扫描相比的优势的数据,但仅在非小细胞支气管肺癌治疗的优化中,特别是在局部区域和远处分期中。

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