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Prognostic and predictive role of CXCR4 IGF-1R and Ezrin expression in localized synovial sarcoma: is chemotaxis important to tumor response?

机译：CXCR4IGF-1R和Ezrin在局部滑膜肉瘤中的预后和预测作用：趋化性对肿瘤反应是否重要？

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BackgroundSynovial sarcoma (SS) is a rare tumor, with dismal survival when metastatic. The role of adjuvant chemotherapy is debated. New prognostic and predictive factors are needed.

机译：背景肉瘤（SS）是一种罕见的肿瘤，转移时生存率低。辅助化疗的作用尚有争议。需要新的预后和预测因素。

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期刊名称 Orphanet Journal of Rare Diseases
作者
Emanuela Palmerini; Maria Serena Benassi; Irene Quattrini; Laura Pazzaglia; Davide Donati; Stefania Benini; Gabriella Gamberi; Marco Gambarotti; Piero Picci; Stefano Ferrari;
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作者单位

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年(卷),期 2015(10),-1
年度 2015
页码 6
总页数 8
原文格式 PDF
正文语种
中图分类医学史;
关键词
CXCR4 IGFR1 Ezrin Synovial sarcoma Prognostic factors Predictive factors;

机译：CXCR4;IGFR1;Ezrin;滑膜肉瘤;预后因素;预测因素;

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专利

1. Prognostic and predictive role of CXCR4, IGF-1R and Ezrin expression in localized synovial sarcoma: is chemotaxis important to tumor response? [J] . Emanuela Palmerini, Maria Serena Benassi, Irene Quattrini, Orphanet journal of rare diseases . 2015,第S1期

机译：CXCR4，IGF-1R和Ezrin在局部滑膜肉瘤中的预后和预测作用：趋化性对肿瘤反应是否重要？
2. The Classic Prognostic Factors Tumor Stage, Tumor Size, and Tumor Grade are the Strongest Predictors of Outcome in Synovial SarcomaNo Role for SSX Fusion Type or Ezrin Expression [J] . Suzan E. ten Heuvel, Harald J. Hoekstra, Esther Bastiaannet, Applied immunohistochemistry and molecular morphology: AIMM . 2009,第3期

机译：经典的预后因素肿瘤分期，肿瘤大小和肿瘤等级是滑膜肉瘤结果的最强预测因子SSX融合类型或Ezrin表达无作用
3. Synovial sarcoma: a multivariate analysis of prognostic factors in 112 patients with primary localized tumors of the extremity. [J] . Lewis JJ, Antonescu CR, Leung DH, Journal of Clinical Oncology . 2000,第10期

机译：滑膜肉瘤：112例四肢原发性局部肿瘤患者的预后因素的多因素分析。
4. HR23b is Expressed in Sarcomas and Gastrointestinal Stromal Tumors and is Associated with Response to HDAC Inhibitor Treatment in a Wide Range of Sarcoma Cell Lines [C] . Michaela Angelika Ihle, Sabine Merkelbach-Bruse, Wolfgang Hartmann, International Molecular Medicine Tri-Conference. . 2015

机译：HR23B以肉瘤和胃肠道基质肿瘤表达，并且与在各种肉瘤细胞系中对HDAC抑制剂治疗的反应相关
5. SYT -SSX1 regulates PIASy activity to cause the overexpression of NCOA3 in synovial sarcoma [D] . Perera, Juanita 2009

机译：SYT -SSX1调节PIASy活性，导致滑膜肉瘤中NCOA3的过度表达
6. Prognostic and predictive value of circulating tumor cells and CXCR4 expression as biomarkers for a CXCR4 peptide antagonist in combination with carboplatin-etoposide in small cell lung cancer: exploratory analysis of a phase II study [O] . Ravi Salgia, R. Waide Weaver, Michael McCleod, -1

机译：循环肿瘤细胞和CXCR4表达作为CXCR4肽拮抗剂联合卡铂-依托泊苷在小细胞肺癌中的生物标志物的预后和预测价值：II期研究的探索性分析
7. Prognostic and predictive role of CXCR4, IGF-1R and Ezrin expression in localized synovial sarcoma: is chemotaxis important to tumor response? [O] . 2015

机译：CXCR4，IGF-1R和Ezrin在局部滑膜肉瘤中的预后和预测作用：趋化性对肿瘤反应是否重要？

Prognostic and predictive role of CXCR4 IGF-1R and Ezrin expression in localized synovial sarcoma: is chemotaxis important to tumor response?

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