Prothrombin Gene G20210A Mutation in Acute Deep Venous Thrombosis Patients with Poor Response to Warfarin Therapy

机译：华法林治疗反应较差的急性深静脉血栓形成患者中凝血酶原基因G20210A突变

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摘要

Aim:The pathogenesis of deep venous thrombosis (DVT) involves an interaction between hereditary and acquired factors. Prothrombin gene mutation is one of the hereditary risk factors. We evaluated the frequency of the prothrombin gene mutation in patients with DVT and its relation to oral warfarin anticoagulant therapy response.

机译：目的：深静脉血栓形成（DVT）的发病机制涉及遗传因素和后天因素之间的相互作用。凝血酶原基因突变是遗传危险因素之一。我们评估了DVT患者中凝血酶原基因突变的频率及其与口服华法林抗凝治疗反应的关系。

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期刊名称 The Open Cardiovascular Medicine Journal
作者
F.M Attia; D.P Mikhailidis; S.A Reffat;
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作者单位

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年(卷),期 2009(3),-1
年度 2009
页码 147–151
总页数 5
原文格式 PDF
正文语种
中图分类心血管疾病;
关键词
Deep venous thrombosis gene mutation prothrombin warfarin.;

机译：深静脉血栓形成;基因突变;凝血酶原;华法林。;

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专利

1. Prothrombin Gene G20210A Mutation in Acute Deep Venous Thrombosis Patients with Poor Response to Warfarin Therapy [J] . F.M. Attia, D.P. Mikhailidis, S.A. Reffat The Open Cardiovascular Medicine Journal . 2009,第1期

机译：华法林治疗反应不良的急性深静脉血栓形成患者中凝血酶原基因G20210A突变
2. Cerebral venous sinus thrombosis as a recurrent thrombotic event in a patient with heterozygous prothrombin G20210A genotype after discontinuation of oral anticoagulation therapy: How long should we treat these patients with warfarin? [J] . Ivana Jukic, Marina Titlic, Ante Tonkic, Journal of Thrombosis and Thrombolysis . 2007,第1期

机译：基因杂合性凝血酶原G20210A基因型患者中止口服口服抗凝治疗后，脑静脉窦血栓形成为复发性血栓形成事件：这些华法林患者应治疗多长时间？
3. Cerebral venous sinus thrombosis as a recurrent thrombotic event in a patient with heterozygous prothrombin G20210A genotype after discontinuation of oral anticoagulation therapy: how long should we treat these patients with warfarin? [J] . Jukic I, Titlic M, Tonkic A, Journal of thrombosis and thrombolysis . 2007,第1期

机译：基因杂合型凝血酶原G20210A基因型患者中止口服口服抗凝治疗后，脑静脉窦血栓形成为复发性血栓事件：这些华法林患者应治疗多长时间？
4. Prothrombin G20210 Mutation and Association with Severe Life Threatening Thrombosis Among Thrombophilic Patients [C] . M. Bellia, S. Sklavou, G. Theodosiades, International Congress on Thrombosis . 2004

机译：血浆患者突变与严重生命危及血栓形成的突变和关联
5. The implications of molecular diagnostics in clinicopathologic correlations in two disease processes: PSA serum levels in acute illnesses, and, prevalence of activated protein C resistance and factor V mutation in patients with thrombosis and in control patients by ethnic group. [D] . Honda, Stacey Ann Akemi. 2002

机译：分子诊断在两种疾病过程中的临床病理相关性中的意义：急性疾病中PSA血清水平，以及血栓形成患者和对照患者（按种族）的活化蛋白C抗性和因子V突变的患病率。
6. Mutation in the Prothrombin Gene G20210A as a Cause of Cerebral Venous Thrombosis [O] . Jorge A. Arroyave, Jairo Quiñones 2012

机译：凝血酶原基因G20210A突变是脑静脉血栓形成的原因
7. Prothrombin Gene G20210A Mutation in Acute Deep Venous Thrombosis Patients with Poor Response to Warfarin Therapy [O] . Attia, F.M, Mikhailidis, D.P, Reffat, S.A 2009

机译：华法林治疗反应较差的急性深静脉血栓形成患者中凝血酶原基因G20210A突变

Prothrombin Gene G20210A Mutation in Acute Deep Venous Thrombosis Patients with Poor Response to Warfarin Therapy

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