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Overexpression of topoisomerase II alpha protein is a factor for poor prognosis in patients with luminal B breast cancer

机译：拓扑异构酶IIα蛋白的过度表达是管腔B型乳腺癌患者预后不良的因素

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BackgroundThe prognostic value and the best method of testing of topoisomerase II alpha (TOP2A) status have not been established in modern tailored therapy based on breast cancer subtype.

机译：背景拓扑异构酶IIα（TOP2A）状态的预后价值和最佳检测方法尚未建立在基于乳腺癌亚型的现代量身定制疗法中。

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期刊名称 Oncotarget
作者
Hideo Shigematsu; Shinji Ozaki; Daisuke Yasui; Hideki Yamamoto; Junichi Zaitsu; Daiki Taniyama; Akihisa Saitou; Kazuya Kuraoka; Taizo Hirata; Kiyomi Taniyama;
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作者单位

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年(卷),期 2018(9),42
年度 2018
页码 26701–26710
总页数 10
原文格式 PDF
正文语种
中图分类肿瘤学;细胞生物学;
关键词
breast cancer topoisomerase IIA prognostic value luminal B;

机译：乳腺癌;拓扑异构酶IIA;预后价值;管腔B;

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专利

1. Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: Heat Shock Protein 90 Overexpression, Ki67 Proliferative Index, and Topoisomerase II-alpha Co-amplification as Predictors of Pathologic Complete Response to Neoadjuvant Chemotherapy With Trastuzumab and Docetaxel [J] . Bria Emilio, Furlanetto Jenny, Carbognin Luisa, Clinical breast cancer . 2015,第1期

机译：人类表皮生长因子受体2阳性乳腺癌：热休克蛋白90过表达，Ki67增殖指数和拓扑异构酶II-alpha联合扩增预测曲妥珠单抗和多西他赛对新辅助化学疗法的病理完全反应。
2. Overexpression of FAM234B Predicts Poor Prognosis in Patients with Luminal Breast Cancer [J] . Lijuan Lyu, Meng Wang, Yi Zheng, Cancer Management and Research . 2020,第3期

机译：FAM234B的过度表达预测腔乳腺癌患者的预后差
3. The prognostic significance of topoisomerase II alpha protein in early stage luminal breast cancer [J] . Xin An, Fei Xu, Rongzhen Luo, BMC Cancer . 2018,第1期

机译：拓扑异构酶IIα蛋白在早期腔内乳腺癌中的预后意义
4. Prognosis prediction of human breast cancer by integrating deep neural network and support vector machine: Supervised feature extraction and classification for breast cancer prognosis prediction [C] . Dongdong Sun, Minghui Wang, Huanqing Feng, International Congress on Image and Signal Processing, BioMedical Engineering and Informatics . 2017

机译：集成深度神经网络和支持向量机的人类乳腺癌预后预测：乳腺癌预后预测的有监督特征提取和分类
5. Breast cancer-specific activation of topoisomerase IIalpha and its application in the tumor-targeting gene therapy. [D] . Day, Chi-Ping. 2005

机译：拓扑异构酶IIalpha的乳腺癌特异性激活及其在肿瘤靶向基因治疗中的应用。
6. Overexpression of FAM234B Predicts Poor Prognosis in Patients with Luminal Breast Cancer [O] . Lijuan Lyu, Meng Wang, Yi Zheng, 2020

机译：FAM234B的过度表达预测腔乳腺癌患者的预后差
7. Overexpression of topoisomerase II alpha protein is a factor for poor prognosis in patients with luminal B breast cancer [O] . Hideo Shigematsu, Shinji Ozaki, Daisuke Yasui, 2018

机译：Topoisomerase IIα蛋白的过度表达是腔B乳腺癌患者预后不良的因素

Overexpression of topoisomerase II alpha protein is a factor for poor prognosis in patients with luminal B breast cancer

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