Neutrophil-to-lymphocyte ratio platelet-to-lymphocyte ratio and their dynamic changes during chemotherapy is useful to predict a more accurate prognosis of advanced biliary tract cancer

摘要

Background and PurposeSystemic inflammation is known to promote carcinogenesis in biliary tract cancer (BTC). Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are indicative of systemic inflammation. We evaluated the clinical significance of systemic inflammation measured by NLR and PLR in patients with advanced BTC. Additionally, we also co-analyzed the dynamics of NLR and PLR during chemotherapy.