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Identification of downstream metastasis-associated target genes regulated by LSD1 in colon cancer cells

机译：LSD1调控的结肠癌细胞下游转移相关靶基因的鉴定

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摘要

PurposeThis study aims to identify downstream target genes regulated by lysine-specific demethylase 1 (LSD1) in colon cancer cells and investigate the molecular mechanisms of LSD1 influencing invasion and metastasis of colon cancer.

机译：目的本研究旨在鉴定赖氨酸特异性脱甲基酶1（LSD1）在结肠癌细胞中调控的下游靶基因，并研究LSD1影响结肠癌侵袭和转移的分子机制。

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期刊名称 Oncotarget
作者
Jiang Chen; Jie Ding; Ziwei Wang; Jian Zhu; Xuejian Wang; Jiyi Du;
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作者单位

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年(卷),期 2017(8),12
年度 2017
页码 19609–19630
总页数 22
原文格式 PDF
正文语种
中图分类肿瘤学;细胞生物学;
关键词
colon cancer LSD1 gene expression profiling target gene epigenomics;

机译：结肠癌;LSD1;基因表达谱;靶基因;表观基因组学;

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专利

1. Identification of metastasis-associated genes by transcriptional profiling of metastatic versus non-metastatic colon cancer cell lines. [J] . De-Lange R, Burtscher H, Jarsch M, Anticancer Research: International Journal of Cancer Research and Treatment . 2001,第4Appa期

机译：通过转移性与非转移性结肠癌细胞系的转录谱鉴定与转移相关的基因。
2. microRNA-30c negatively regulates endometrial cancer cells by targeting metastasis-associated gene-1 [J] . ZhouH., XuX., XunQ., Oncology reports . 2012,第3期

机译：microRNA-30c通过靶向转移相关基因1负调控子宫内膜癌细胞
3. Overexpression of circular RNA hsa_circ_0001038 promotes cervical cancer cell progression by acting as a ceRNA for miR-337-3p to regulate cyclin-M3 and metastasis-associated in colon cancer 1 expression [J] . Gene: An International Journal Focusing on Gene Cloning and Gene Structure and Function . 2020,第期

机译：圆形RNA HSA_CIRC_0001038的过度表达通过作为MIR-337-3P的CERNA来调节细胞周期蛋白-M3和结肠癌相关联的宫颈癌细胞进展1表达
4. Identification of Genes Regulated by the Antiprogestin, Onapristone, in Breast Cancer Cells using Microarray Analysis [C] . Simon J. Crook, J. David Brook, Anette Sommer, International Symposium on Hormonal Carcinogenesis . 2005

机译：鉴定使用微阵列分析乳腺癌细胞抗胃癌，onapristone调节的基因
5. Nkx2.2 regulated target genes and downstream molecular mechanisms necessary for pancreas cell type specification. [D] . Anderson, Keith R. 2009

机译：Nkx2.2调控胰腺细胞类型规范必需的靶基因和下游分子机制。
6. MicroRNA-432 is downregulated in osteosarcoma and inhibits cell proliferation and invasion by directly targeting metastasis-associated in colon cancer-1 [O] . Dengkun Lv, Zhen Zhen, Defa Huang -1

机译：MicroRNA-432在骨肉瘤中被下调并通过直接靶向结肠癌1中相关的转移来抑制细胞增殖和侵袭
7. Identification of downstream metastasis-associated target genes regulated by LSD1 in colon cancer cells [O] . Jiang Chen, Jie Ding, Ziwei Wang, 2017

机译：鉴定CONON癌细胞中LSD1调节的下游转移相关靶基因
8. Identification of New EGR1 Target Genes That Regulate Radiation Responses in Prostate Cancer Cells [R] . Arora, S. 2006

机译：鉴定调节前列腺癌细胞辐射反应的新EGR1靶基因

Identification of downstream metastasis-associated target genes regulated by LSD1 in colon cancer cells

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