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A Phase II Trial Evaluating the Efficacy and Safety of Efavirenz in Metastatic Castration-Resistant Prostate Cancer

机译：评价依法韦伦在转移性去势抵抗性前列腺癌中的疗效和安全性的第二阶段试验

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摘要

Background.Preclinical studies demonstrated that non-nucleoside reverse transcriptase inhibitors used for the treatment of HIV could antagonize tumor development. This led us to assess the efficacy of efavirenz in patients with metastatic castration-resistant prostate cancer (mCRPC) in a multicenter phase II study.

机译：背景：临床前研究表明，用于治疗HIV的非核苷类逆转录酶抑制剂可以拮抗肿瘤的发展。因此，我们在一项多中心II期研究中评估了依非韦伦对转移性去势抵抗性前列腺癌（mCRPC）患者的疗效。

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期刊名称 The Oncologist
作者
Nadine Houédé; Marina Pulido; Loic Mourey; Florence Joly; Jean-Marc Ferrero; Carine Bellera; Frank Priou; Caroline Lalet; Audrey Laroche-Clary; Mireille Canal Raffin; François Ichas; Alain Puech; Pierre Vincenzo Piazza;
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年(卷),期 2014(19),12
年度 2014
页码 1227–1228
总页数 2
原文格式 PDF
正文语种
中图分类肿瘤学;
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专利

1. A Phase II Trial Evaluating the Efficacy and Safety of Efavirenz in Metastatic Castration-Resistant Prostate Cancer [J] . Houede Nadine, Pulido Marina, Mourey Loic, The oncologist . 2014,第12期

机译：评价依夫韦仑在转移性去势抵抗性前列腺癌中的疗效和安全性的第二阶段试验
2. A Phase II Trial Evaluating the Efficacy and Safety of Efavirenz in Metastatic Castration-Resistant Prostate Cancer [J] . Alain Puech, Audrey Laroche-Clary, Carine Bellera, The oncologist . 2014,第12期

机译：评价依夫韦仑在转移性去势抵抗性前列腺癌中的疗效和安全性的第二阶段试验
3. Final safety and efficacy analysis of the specific endothelin A receptor antagonist zibotentan (ZD4054) in patients with metastatic castration-resistant prostate cancer and bone metastases who were pain-free or mildly symptomatic for pain: a double-blind, placebo-controlled, randomized Phase II trial [J] . Nicholas D. James, Armelle Caty, Heather Payne, BJU International . 2010,第7期

机译：特定的内皮素A受体拮抗剂Zibotentan（ZD4054）在无痛或轻度疼痛症状的转移性去势抵抗性前列腺癌和骨转移患者中的最终安全性和有效性分析：双盲，安慰剂对照，随机分期二审
4. Phase I/II clinical trials on the effect of weekly paclitaxel (wPTX) and wPTX containing combination regimens for advanced and metastatic gastric cancer -ECRIN group studies [C] . Sakamoto J, Kodera Y, Kobayashi M, International Gastric Cancer Congress . 2009

机译：I / II期临床试验关于每周紫杉醇（WPTX）和WPTX含有晚期和转移性胃癌组合方案的临床试验 - 分泌组研究
5. Muscle Cross-Sectional Area Is Improved and Physical Funciton Is Maintained After Home-Based Exercise in Men with Metastatic Castration-Resistant Prostate Cancer Undergoing Androgen Deprivation Therapy [D] . Alzer, Mohamdod Saber. 2020

机译：改善肌横截面积，并且在具有转移阉割的前列腺癌接受雄激素剥夺治疗的男性中的男性锻炼之后，将物理静脉凝集维持
6. Once-daily Dasatinib: Expansion of Phase II Study Evaluating Safety and Efficacy of Dasatinib in Patients With Metastatic Castration-resistant Prostate Cancer [O] . Evan Y. Yu, Christophe Massard, Mitchell E. Gross, -1

机译：每日一次达沙替尼：Ⅱ期研究评估安全性和达沙替尼疗效治疗转移性去势抵抗性前列腺癌的扩展
7. Once-daily Dasatinib: Expansion of Phase II Study Evaluating Safety and Efficacy of Dasatinib in Patients With Metastatic Castration-resistant Prostate Cancer [O] . Evan Y. Yu, Christophe Massard, Mitchell E. Gross, 2011

机译：一旦日常Dasatinib：扩展II期研究评估Dasatinib在转移阉割抗阉割前列腺癌患者中的安全性和疗效

A Phase II Trial Evaluating the Efficacy and Safety of Efavirenz in Metastatic Castration-Resistant Prostate Cancer

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