首页> 美国卫生研究院文献>Neurologia medico-chirurgica >Surgical Outcome of Laminoplasty for Cervical Spondylotic Myelopathy in an Elderly Population – Potentiality for Effective Early Surgical Intervention: A Meta-analysis
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Surgical Outcome of Laminoplasty for Cervical Spondylotic Myelopathy in an Elderly Population – Potentiality for Effective Early Surgical Intervention: A Meta-analysis

机译:椎弓根成形术治疗老年人颈椎病的手术效果-有效早期手术干预的潜力:一项荟萃分析

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摘要

A systematic review and meta-analysis was conducted to determine differences in surgical outcomes of laminoplasty for cervical spondylotic myelopathy (CSM) between elderly and non-elderly patients. PubMed and Google Scholar searches were performed using several key words and phrases related to cervical laminoplasty in elderly populations. Included studies were written in English, addressed laminoplasty for cervical spondylotic myelopathy, and evaluated outcomes of the treatment. Statistical analysis was performed using a random-effect model. The heterogeneity of the studies was assessed using Cochran’s Q statistic and I2 statistic, and a funnel plot was constructed to evaluate publication bias. The search initially identified 255 articles on this topic. Nine clinical studies that met all inclusion criteria were included in the meta-analysis. A total of 1817 patients in these studies underwent cervical laminoplasty. Elderly patients had lower preoperative and postoperative Japanese Orthopedic Association (JOA) scores, and lower recovery rates based on JOA scores. Shorter operation times and reductions in intraoperative blood loss were found in the elderly group compared to the non-elderly group. The incidence of C5 palsy was not different between these groups. We here report the differences in surgical outcomes of laminoplasty for CSM through systematic review and meta-analysis. This report found poor surgical outcomes and lower preoperative JOA scores in elderly patients. Therefore, early surgical intervention may be recommended in elderly patients with CSM.
机译:进行了系统的回顾和荟萃分析,以确定老年和非老年患者在椎板成形术治疗颈椎病(CSM)方面的差异。 PubMed和Google Scholar搜索使用了几个与老年人口颈椎椎体成形术相关的关键词。包括的研究用英语撰写,针对颈椎病性脊髓病的椎板成形术,并评估了治疗结果。使用随机效应模型进行统计分析。使用Cochran的Q统计量和I 2 统计量对研究的异质性进行了评估,并构建了漏斗图以评估出版偏倚。搜索最初确定了有关该主题的255篇文章。荟萃分析包括九项符合所有入选标准的临床研究。在这些研究中,共有1817例患者接受了颈椎椎体隆凸成形术。老年患者术前和术后日本骨科协会(JOA)得分较低,而基于JOA得分的康复率较低。与非老年组相比,老年组的手术时间更短,术中出血减少了。这些组之间C5麻痹的发生率没有差异。我们在这里通过系统评价和荟萃分析报告了CSM椎板成形术的外科手术结果的差异。该报告发现老年患者手术效果差,术前JOA评分较低。因此,老年CSM患者可能建议早期手术干预。

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