GERM-09. WHOLE VENTRICULAR IRRADIATION FOR INTRACRANIAL GERM CELL TUMORS: DOSIMETRIC COMPARISON OF PENCIL BEAM SCANNED PROTONS VS. IMRT

摘要

BACKGROUNDWhole ventricular irradiation (WV-RT) followed by a boost to the tumor bed (WV-RT/TB) is recommended for localized intracranial germ cell tumors (GCT). As the eloquent brain areas are mainly in direct vicinity of the target volume, it is unknown if proton therapy indeed substantially spares these organs at risk (OAR). Therefore, a dosimetric comparison study of WV-RT/TB was conducted to assess whether protons or modern photon radiotherapy achieve better critical organ sparing.