P04.08 GLIOTRAIN: Exploiting Glioblastoma intractability to address European research training needs in translational brain tumour research cancer systems medicine and integrative multi-omics

摘要

BackgroundGlioblastoma (GBM) is the most frequent, aggressive and lethal of all brain tumours. 85% of patients die within two years. Thus, new treatment options are urgently required. To address this deficit, the Royal College of Surgeons in Ireland (RCSI) is leading a major new programme “GLIOTRAIN” () that aims to identify new therapeutic strategies, while implementing state of the art genomics and systems medicine approaches to unravel resistance mechanisms. Here, we introduce the GLIOTRAIN initiative which received €3.8 million in September 2017 from the European Commission’s Horizon 2020 Marie Skłodowska-Curie Actions programme.