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Association of CFH LOC387715 and HTRA1 polymorphisms with exudative age-related macular degeneration in a northern Chinese population

机译:CFHLOC387715和HTRA1多态性与中国北方人口与年龄相关的渗出性黄斑变性的相关性

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摘要

PurposeVariants in complement factor H (CFH), the hypothetical LOC387715, and the high-temperature requirement A-1 (HTRA1) genes have been reported to be associated with age-related macular degeneration (AMD). The purpose of this study was to investigate the association of reported common single-nucleotide polymorphisms (SNPs) in CFH, LOC387715, and HTRA1 with exudative AMD in a northern Chinese population.
机译:目的据报道补体因子H(CFH),假设的LOC387715和高温需求A-1(HTRA1)基因的变异与年龄相关性黄斑变性(AMD)相关。这项研究的目的是调查中国北方人口中CFH,LOC387715和HTRA1中报告的常见单核苷酸多态性(SNP)与渗出性AMD的关联。

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