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A Novel Colorimetric Fluorescent Probe for SO2 and Its Application in Living Cells Imaging

机译:一种新型的SO2比色荧光探针及其在活细胞成像中的应用

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摘要

A novel chromenylium-based fluorescent probe was exploited for sulphur dioxide (SO2) detecting. The probe displayed a remarkable fluorescence turn-on response towards SO2 based on the nucleophilic addition reaction to the carbon-carbon double bond with 105 nm Stock shift. The probe was successfully applied for the quantification of SO2.The linear detection range was from 0–160 μM with the detection limit as low as 99.27 nM. It also exhibited high selectivity for SO2 than other reactive species and amino acids. Furthermore, cell staining experiments indicated that the probe was cell membrane permeable and could be used for high-performance imaging of SO2 in living cells. The superior properties of the probe made it highly promising for use in chemical and biological applications.
机译:一种新型的基于氧化铬的荧光探针被用于二氧化硫(SO2)检测。基于对105 nm储层位移的碳-碳双键的亲核加成反应,该探针对SO2表现出显着的荧光开启响应。该探针已成功应用于二氧化硫的定量分析。线性检测范围为0-160μM,检测限低至99.27 nM。与其他反应物种和氨基酸相比,它对SO2的选择性也高。此外,细胞染色实验表明该探针可穿透细胞膜,可用于活细胞中SO2的高性能成像。探针的优越性能使其在化学和生物学应用中具有广阔的前景。

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