An Amidochlorin-Based Colorimetric Fluorescent Probe for Selective Cu2+ Detection

摘要

The design and synthesis of selective and sensitive chemosensors for the quantification of environmentally and biologically important ionic species has attracted widespread attention. Amidochlorin p6 (>ACP); an effective colorimetric and fluorescent probe for copper ions (Cu²⁺) in aqueous solution derived from methyl pheophorbide-a (MPa) was designed and synthesized. A remarkable color change from pale yellow to blue was easily observed by the naked eye upon addition of Cu²⁺; and a fluorescence quenching was also determined. The research of fluorescent quenching of >ACP-Cu²⁺ complexation showed the detection limit was 7.5 × 10⁻⁸ mol/L; which suggested that >ACP can act as a high sensitive probe for Cu²⁺ and can be used to quantitatively detect low levels of Cu²⁺ in aqueous solution. In aqueous solution the probe exhibits excellent selectivity and sensitivity toward Cu²⁺ ions over other metal ions (M = Zn²⁺; Ni²⁺; Ba²⁺; Ag⁺; Co²⁺; Na⁺; K⁺; Mg²⁺; Cd²⁺; Pb²⁺; Mn²⁺; Fe³⁺; and Ca²⁺). The obvious change from pale yellow to blue upon the addition of Cu²⁺ could make it a suitable “naked eye” indicator for Cu²⁺.