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Modified Polyacrylic Acid-Zinc Composites: Synthesis Characterization and Biological Activity

机译:改性聚丙烯酸-锌复合材料的合成表征和生物活性

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摘要

Polyacrylic acid (PAA) is an important industrial chemical, which has been extensively applied in various fields, including for several biomedical purposes. In this study, we report the synthesis and modification of this polymer with various phenol imides, such as succinimide, phthalimide and 1,8-naphthalimide. The as-synthesized derivatives were used to prepare polymer metal composites by the reaction with Zn+2. These composites were characterized by using various techniques, including NMR, FT-IR, TGA, SEM and DSC. The as-prepared PAA-based composites were further evaluated for their anti-microbial properties against various pathogens, which include both Gram-positive and Gram-negative bacteria and different fungal strains. The synthesized composites have displayed considerable biocidal properties, ranging from mild to moderate activities against different strains tested.
机译:聚丙烯酸(PAA)是一种重要的工业化学品,已广泛应用于各个领域,包括用于多种生物医学目的。在这项研究中,我们报告了该聚合物与各种酚酰亚胺(如琥珀酰亚胺,邻苯二甲酰亚胺和1,8-萘二甲酰亚胺)的合成和改性。所合成的衍生物通过与Zn +2 反应制备聚合物金属复合材料。这些复合材料通过使用各种技术进行表征,包括NMR,FT-IR,TGA,SEM和DSC。进一步评估了所制备的基于PAA的复合材料对各种病原体(包括革兰氏阳性菌和革兰氏阴性菌以及不同的真菌菌株)的抗微生物特性。合成的复合材料显示出可观的杀菌性能,对不同的测试菌株具有中等至中等的活性。

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