Isolation and Characterization of Silyl Enol Ether Intermediates in the Synthesis of 56910–Tetrahydro-78-benzocyclooctene-dione

摘要

The 5,6,9,10-tetrahydro-7,8-benzocyclooctenedione >4 has been synthesized through fragmentation of a bicyclo[4.2.0]octane system using an acyloin reaction on the trans-2,3-dicarboethoxy-1,2,3,4-tetrahydronaphthalene >1 in the presence of trimethyl-chlorosilane (TMCS). The two intermediates of this reaction, bis(trimethylsiloxy) derivatives >2 and >3, have been isolated and characterized.