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Fabrication and Characterization of Micro-Nano Electrodes for Implantable BCI

机译:植入式BCI微纳米电极的制备与表征

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摘要

Signal recording and stimulation with high spatial and temporal resolution are of increasing interest with the development of implantable brain-computer interfaces (BCIs). However, implantable BCI technology still faces challenges in the biocompatibility and long-term stability of devices after implantation. Due to the cone structure, needle electrodes have advantages in the biocompatibility and stability as nerve recording electrodes. This paper develops the fabrication of Ag needle microano electrodes with a laser-assisted pulling method and modifies the electrode surface by electrochemical oxidation. A significant impedance reduction of the modified Ag/AgCl electrodes compared to the Ag electrodes is demonstrated by the electrochemical impedance spectrum (EIS). Furthermore, the stability of modified Ag/AgCl electrodes is confirmed by cyclic voltammogram (CV) scanning. These findings suggest that these microano electrodes have a great application prospect in neural interfaces.
机译:随着植入式脑机接口(BCI)的发展,具有高时空分辨率的信号记录和刺激越来越引起人们的关注。但是,植入式BCI技术在植入后仍然具有生物相容性和设备长期稳定性方面的挑战。由于具有锥形结构,所以针状电极具有与神经记录电极相同的生物相容性和稳定性。本文研究了利用激光辅助拉制法制备银针微/纳米电极的方法,并通过电化学氧化修饰电极表面。电化学阻抗谱(EIS)证明了与Ag电极相比,改性Ag / AgCl电极的阻抗显着降低。此外,修饰的Ag / AgCl电极的稳定性通过循环伏安图(CV)扫描得到证实。这些发现表明,这些微/纳米电极在神经界面中具有广阔的应用前景。

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