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Electrochemical and Optical Biosensors for the Detection of Campylobacter and Listeria: An Update Look

机译:用于检测弯曲杆菌和李斯特菌的电化学和光学生物传感器:最新外观

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摘要

Foodborne safety has aroused tremendous research interest in recent years because of a global public health problem. The rapid and precise detection of foodborne pathogens can reduce significantly infection diseases and save lives by the early initiation of an effective treatment. This review highlights current advances in the development of biosensors for detection of Campylobacter spp. and Listeria monocytogenes that are the most common causes of zoonosis. The consumption of pathogen contaminated food is responsible for humans hospitalization and death. The attention focused on the recognition elements such as antibodies (Ab), DNA probes and aptamers able to recognize cells, amplicons, and specific genes from different samples like bacteria, food, environment and clinical samples. Moreover, the review focused on two main signal-transducing mechanisms, i.e., electrochemical, measuring an amperometric, potentiometric and impedimetric signal; and optical, measuring a light signal by OLED (Organic Light Emitting Diode), SPR (Surface Plasmon Resonance), and Optical fiber. We expect that high-performance of devices being developed through basic research will find extensive applications in environmental monitoring, biomedical diagnostics, and food safety.
机译:由于全球公共卫生问题,近年来食源性安全引起了巨大的研究兴趣。食源性病原体的快速精确检测可以通过尽早开始有效的治疗来显着减少感染疾病并挽救生命。这篇综述重点介绍了用于检测弯曲杆菌属的生物传感器的最新进展。和单核细胞增生李斯特菌是人畜共患病的最常见原因。食用被病原体污染的食物会导致人类住院和死亡。注意力集中在识别元件上,例如抗体(Ab),DNA探针和适体,它们能够识别来自细菌,食品,环境和临床样品等不同样品的细胞,扩增子和特定基因。此外,该综述集中在两种主要的信号传导机制,即电化学的,测量安培,电位和阻抗信号的机制。光学,通过OLED(有机发光二极管),SPR(表面等离子体共振)和光纤测量光信号。我们希望通过基础研究开发的高性能设备将在环境监测,生物医学诊断和食品安全方面得到广泛的应用。

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