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Computational simulation of a new system modelling ions electromigration through biological membranes

机译:离子通过生物膜电迁移的新系统的计算仿真

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摘要

BackgroundThe interest in cell membrane has grown drastically for their important role as controllers of biological functions in health and illness. In fact most important physiological processes are intimately related to the transport ability of the membrane, such as cell adhesion, cell signaling and immune defense. Furthermore, ion migration is connected with life-threatening pathologies such as metastases and atherosclerosis. Consequently, a large amount of research is consecrated to this topic. To better understand cell membranes, more accurate models of ionic flux are required and also their computational simulations.
机译:背景技术由于细胞膜作为健康和疾病中生物功能的控制者的重要作用,人们对细胞膜的兴趣急剧增长。实际上,最重要的生理过程与膜的运输能力密切相关,例如细胞粘附,细胞信号传导和免疫防御。此外,离子迁移与威胁生命的病理如转移和动脉粥样硬化有关。因此,对该主题进行了大量研究。为了更好地了解细胞膜,需要更精确的离子通量模型及其计算模拟。

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