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Venous thromboprophylaxis in UK medical inpatients

机译:英国医疗住院患者的静脉血栓预防

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摘要

We prospectively assessed the implementation of venous thromboembolism (VTE) prophylaxis guidelines and the impact of grand round presentation of the datain changing clinical practice. Two NHS teaching hospitals were studied for 24 months from January 2003. Patients were risk stratified according to the THRIFT (thromboembolic risk factor) consensus group guidelines and compared with the recommendations of the THRIFT and ACCP (American College of Chest Physicians) consensus groups. Six months following presentation of the initial results, a further analysis was made to assess changes in clinical practice.1128 patients were assessed of whom 1062 satisfied the inclusion criteria for thromboprophylaxis. 89% of all patients were stratified as having high or moderate riskof developing VTE. Of these only 28% were prescribed some form of thromboprophylaxis—4% received the THRIFT-recommended and 22% received the ACCP-recommended thromboprophylaxis. The vast majority (72%) received no thromboprophylaxis at all. Reassessment, following data presentation at grandrounds, showed a significant increase to 31% inpatients receiving THRIFT (P<0.0001) and ACCP (P=0.002) recommended thromboprophylaxis. However,the proportion of patients receiving no form of prophylaxis barely changed (72% to 69%: P=0.59).We found a gross underutilization of thromboprophylaxis in hospitalized medical patients. A simple grand-round presentation of the data and recommended guidelines to clinicians significantly increased the proportion of patients receiving recommended thromboprophylaxis but did not increasethe overall proportion of patients receiving it. Wetherefore conclude that a single presentation of guidelines is not enough to achieve the desired levels. Such presentations may only serve to make DVT (deepvenous thromboembolism) aware clinicians prescribe prophylaxis more accurately.
机译:我们前瞻性地评估了静脉血栓栓塞(VTE)预防指南的实施情况以及数据的全面展示在不断变化的临床实践中的影响。自2003年1月起,对两家NHS教学医院进行了为期24个月的研究。根据THRIFT(血栓栓塞危险因素)共识小组指南对患者进行风险分层,并与THRIFT和ACCP(美国胸科医师学会)共识小组的建议进行比较。初步结果发表六个月后,进行了进一步分析以评估临床实践的变化。评估了1128例患者,其中1062例符合血栓预防的纳入标准。所有患者中有89%被分层为具有发展为VTE的高风险或中度风险。在这些患者中,只有28%的患者接受了某种形式的血栓预防治疗-4%的患者接受了THRIFT推荐,22%的患者接受了ACCP建议的预防血栓形成。绝大多数(72%)完全没有进行血栓预防。在Grandrounds进行数据展示后,重新评估显示接受THRIFT(P <0.0001)和ACCP(P = 0.002)建议进行血栓预防的住院患者显着增加。然而,未接受任何形式的预防的患者比例几乎没有变化(72%至69%:P = 0.59)。我们发现住院医疗患者的血栓预防利用率未得到充分利用。对临床医生进行的简单数据轮全面介绍和推荐指南,显着增加了接受推荐血栓预防的患者比例,但并未增加接受血栓预防的总体比例。因此,我们得出的结论是,仅仅介绍一份准则不足以达到期望的水平。此类介绍仅可用于使DVT(深静脉血栓栓塞)意识的临床医生更准确地规定预防措施。

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