首页> 美国卫生研究院文献>Lipids in Health and Disease >Phytanic acid activates NADPH oxidase through transactivation of epidermal growth factor receptor in vascular smooth muscle cells

【2h】

Phytanic acid activates NADPH oxidase through transactivation of epidermal growth factor receptor in vascular smooth muscle cells

机译：植烷酸通过表皮生长因子受体在血管平滑肌细胞中的反式激活激活NADPH氧化酶

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

BackgroundPhytanic acid (PA) has been implicated in development of cancer and its defective metabolism is known to cause life-threatening conditions, such as Refsum disease, in children. To explore molecular mechanisms of phytanic acid-induced cellular pathology, we investigated its effect on NADPH oxidase (NOX) and epidermal growth factor receptor (EGFR) in rat aortic smooth muscle cells (RASMC).

机译：背景乙二酸（PA）与癌症的发展有关，已知其代谢不良会导致威胁儿童的生命，例如Refsum疾病。为了探索植酸诱导细胞病理的分子机制，我们研究了其对大鼠主动脉平滑肌细胞（RASMC）中NADPH氧化酶（NOX）和表皮生长因子受体（EGFR）的影响。

著录项

期刊名称 Lipids in Health and Disease
作者
Gursev S. Dhaunsi; Mayra Alsaeid; Saghir Akhtar;
展开▼
作者单位

展开▼
年(卷),期 2016(15),-1
年度 2016
页码 105
总页数 6
原文格式 PDF
正文语种
中图分类分子生物学 ;
关键词
Phytanic acid Aortic smooth muscle NADPH oxidase EGFR;

机译：植酸;主动脉平滑肌;NADPH氧化酶;EGFR;

相似文献

外文文献
中文文献
专利

1. Angiotensin II-induced migration of vascular smooth muscle cells is mediated by p38 mitogen-activated protein kinase-activated c-Src through spleen tyrosine kinase and epidermal growth factor receptor transactivation. [J] . Mugabe BE, Yaghini FA, Song C The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2010 ,第1期

机译：血管紧张素II诱导的血管平滑肌细胞迁移是通过p38丝裂原激活的蛋白激酶激活的c-Src通过脾酪氨酸激酶和表皮生长因子受体反式激活介导的。
2. Angiotensin II-dependent growth of vascular smooth muscle cells requires transactivation of the epidermal growth factor receptor via a cytosolic phospholipase A_2-mediated release of arachidonic acid [J] . Freeman E.J., Sheakley M.L., Clements R.J. Archives of Biochemistry and Biophysics . 2010 ,第1期

机译：血管平滑肌细胞的血管紧张素II依赖性生长需要通过胞质磷脂酶A_2介导的花生四烯酸释放来激活表皮生长因子受体
3. Plasma Kallikrein Promotes Epidermal Growth Factor Receptor Transactivation and Signaling in Vascular Smooth Muscle through Direct Activation of Protease-activated Receptors [J] . Rany T. Abdallah, Joo-Seob Keum, Mi-Hye Lee, The Journal of biological chemistry . 2010 ,第期

机译：通过直接激活蛋白酶活化受体，血浆Kallikrein促进表皮生长因子受体转移和信号在血管平滑肌中的信号
4. Cyclic strain induces ES cell differentiation into vascular smooth muscle cells via PDGF receptor ?? activation [C] . Yamamoto Kimiko, Shimizu Nobutaka, Obi Syotaro, International Symposium on Micro-NanoMechatronics and Human Science . 2008

机译：循环菌株通过PDGF受体诱导ES细胞分化成血管平滑肌细胞??激活
5. Molecular regulation of Nox1 NADPH oxidase in vascular smooth muscle cell activation. [D] . Streeter, Jennifer Lee. 2015

机译：Nox1 NADPH氧化酶在血管平滑肌细胞活化中的分子调控。
6. Angiotensin II-Induced Migration of Vascular Smooth Muscle Cells Is Mediated by p38 Mitogen-Activated Protein Kinase-Activated c-Src Through Spleen Tyrosine Kinase and Epidermal Growth Factor Receptor Transactivation [O] . Benon E. Mugabe, Fariborz A. Yaghini, Chi Young Song, -1

机译：血管紧张素II诱导的血管平滑肌细胞迁移是通过脾酪氨酸激酶和表皮生长因子受体反式激活的p38丝裂原活化的蛋白激酶活化的c-Src介导的。
7. Phytanic acid activates NADPH oxidase through transactivation of epidermal growth factor receptor in vascular smooth muscle cells [O] . Gursev S. Dhaunsi, Mayra Alsaeid, Saghir Akhtar 2016

机译：植烷酸通过表皮生长因子受体在血管平滑肌细胞中的反式激活激活NADPH氧化酶

Phytanic acid activates NADPH oxidase through transactivation of epidermal growth factor receptor in vascular smooth muscle cells

摘要

著录项

相似文献

相关主题

期刊订阅