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Effect of SORT1 APOB and APOE polymorphisms on LDL-C and coronary heart disease in Pakistani subjects and their comparison with Northwick Park Heart Study II

机译：SORT1APOB和APOE多态性对巴基斯坦受试者LDL-C和冠心病的影响以及与Northwick Park心脏研究II的比较

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BackgroundMany SNPs have been identified in genes regulating LDL-C metabolism, but whether their influence is similar in subjects from different ethnicities is unclear. Effect of 4 such SNPs on LDL-C and coronary heart disease (CHD) was examined in Pakistani subjects and was compared with middle aged UK men from Northwick Park Heart Study II (NPHSII).

机译：背景技术已经在调节LDL-C代谢的基因中鉴定出许多SNP，但尚不清楚它们在不同种族的受试者中的影响是否相似。在巴基斯坦受试者中检查了4种这样的SNP对LDL-C和冠心病（CHD）的作用，并与Northwick Park心脏研究II（NPHSII）的中年英国男性进行了比较。

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期刊名称 Lipids in Health and Disease
作者
Saleem Ullah Shahid; Shabana ᅟ; Jackie A. Cooper; Katherine E. Beaney; Kawah Li; Abdul Rehman; Stephen Eric Humphries;
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作者单位

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年(卷),期 2016(15),-1
年度 2016
页码 83
总页数 9
原文格式 PDF
正文语种
中图分类分子生物学;
关键词
LDL-C SORT1 APOB APOE Gene score;

机译：LDL-C;SORT1;APOB;APOE;基因得分;

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专利

1. Human paraoxonase gene cluster polymorphisms as predictors of coronary heart disease risk in the prospective Northwick Park Heart Study II [J] . Kirsty S. Robertson, Emma Hawe, George J. Miller, Biochimica et biophysica acta. Molecular basis of disease: BBA . 2003,第3期

机译：人类对氧磷酶基因簇多态性可预测前瞻性Northwick Park心脏研究II中的冠心病风险
2. Distinguishing between those dying suddenly or not suddenly from coronary heart disease: long-term prospective results from the Northwick Park Heart Study [J] . Douglas Chamberlain, Tom Meade, Tim Clayton Open Heart . 2016,第2期

机译：在突然死于或不是突然死于冠心病的人之间进行区分：Northwick Park心脏研究的长期前瞻性结果
3. Peak flow rate and death due to coronary heart disease: 30-year results from the Northwick Park Heart cohort study [J] . Bianca L De Stavola, Elizabeth L Turner, Tim C Clayton, Open Heart . 2014,第1期

机译：峰值流速和冠心病导致的死亡：Northwick Park心脏队列研究的30年结果
4. Nebivolol influence the exercise tolerance, endothelial function and skeletal musculature condition in pts. with coronary heart disease complicated by heart failure II-III [C] . Komissarova S., Vaikhanskaya T., Zolotuchina S., International Congress on Coronary Artery Disease . 2009

机译：Nebivolol影响PTS中的运动耐受性，内皮功能和骨骼肌肌肉状况。冠心病与心力衰竭合并的冠心病II-III
5. Homocysteine, folate, vitamin B-12, lifestyle, and risk of coronary heart disease in Jordanian subjects [D] . Mashal, Rima H. 2002

机译：同型半胱氨酸，叶酸，维生素B-12，生活方式和约旦受试者的冠心病风险
6. Original research article: Distinguishing between those dying suddenly or not suddenly from coronary heart disease: long-term prospective results from the Northwick Park Heart Study [O] . Tom Meade, Tim Clayton, Douglas Chamberlain 2016

机译：原始研究文章：辨别那些突然死于或不是突然死于冠心病的人：Northwick Park心脏研究的长期预期结果
7. Effect of , and polymorphisms on LDL-C and coronary heart disease in Pakistani subjects and their comparison with Northwick Park Heart Study II [O] . 2016

机译：多态性和多态性对巴基斯坦受试者LDL-C和冠心病的影响以及与Northwick Park心脏研究II的比较

Effect of SORT1 APOB and APOE polymorphisms on LDL-C and coronary heart disease in Pakistani subjects and their comparison with Northwick Park Heart Study II

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