Analysis of antibody profiles in symptomatic malaria in three sentinel sites of Ivory Coast by using multiplex fluorescent magnetic bead-based serological assay (MAGPIX™)

摘要

BackgroundAdvances in malaria control have reduced the burden of disease resulting from exposure to parasite infections. The consequences on naturally acquired immunity are unclear. A magnetic bead-based immunoassay (MBA) to assess antibody levels in populations living in endemic areas was previously evaluated. In this study, the effect of clinical attacks on immunity was analysed in three sentinel sites of Ivory Coast.