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Delayed anemia assessment in patients treated with oral artemisinin derivatives for uncomplicated malaria: a pooled analysis of clinical trials data from Mali

机译:口服青蒿素衍生物治疗无并发症疟疾的患者延迟贫血评估:来自马里的临床试验数据汇总分析

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摘要

BackgroundIn sub-Saharan Africa, artemisinin-based combination therapy (ACT) and injectable artesunate are the first-line treatments for uncomplicated and severe Plasmodium falciparum malaria, respectively. However, recent studies suggest that delayed anaemia is associated with these treatments in non-immune travellers. This paper aimed to assess the risk factors associated with delayed anaemia after falciparum malaria treatment with artemisinin-containing drugs in malaria-endemic populations.
机译:背景技术在撒哈拉以南非洲地区,基于青蒿素的联合治疗(ACT)和可注射青蒿琥酯分别是单纯性和严重恶性疟原虫疟疾的一线治疗。但是,最近的研究表明,在非免疫旅行者中,延迟性贫血与这些治疗有关。本文旨在评估在疟疾流行人群中使用含青蒿素的药物治疗恶性疟疾后恶性血液病与延迟性贫血相关的危险因素。

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