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Patch Testing in Suspected Allergic Contact Dermatitis to Cosmetics

机译:化妆品中疑似过敏性接触性皮炎的贴剂测试

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摘要

Background. Increasing use of cosmetics has contributed to a rise in the incidence of allergic contact dermatitis (ACD) to cosmetics. It is estimated that 1–5.4% of the population is sensitized to a cosmetic ingredient. Patch testing helps to confirm the presence of an allergy and to identify the actual allergens which are chemical mixtures of various ingredients. Objectives. The aims of this study are to perform patch testing in suspected ACD to cosmetics and to identify the most common allergen and cosmetic product causing dermatitis. Methods. Fifty patients with suspected ACD to cosmetics were patch-tested with 38 antigens of the Indian Cosmetic Series and 12 antigens of the Indian Standard Series. Results. The majority (58%) of patients belonged to the 21–40 years age group. The presence of ACD to cosmetics was confirmed in 38 (76%) patients. Face creams (20%), hair dyes (14%), and soaps (12%) were the most commonly implicated. The most common allergens identified were gallate mix (40%), cetrimide (28%), and thiomersal (20%). Out of a total of 2531 patches applied, positive reactions were obtained in 3.75%. Conclusion. Incidence of ACD to cosmetics was greater in females. Face creams and hair dyes were the most common cosmetic products implicated. The principal allergens were gallate mix, cetrimide, and thiomersal.
机译:背景。化妆品使用的增加已导致对化妆品的过敏性接触性皮炎(ACD)的发生率上升。据估计,人口的1–5.4%对化妆品成分敏感。补丁测试有助于确认过敏的存在,并确定实际的过敏原,这些过敏原是各种成分的化学混合物。目标。这项研究的目的是对可疑的ACD化妆品进行补丁测试,并确定引起皮炎的最常见的过敏原和化妆品。方法。用印度化妆品系列的38种抗原和印度标准系列的12种抗原对50名怀疑患有ACD化妆品的患者进行了贴片测试。结果。大多数患者(58%)属于21-40岁年龄组。在38名(76%)患者中证实了化妆品中存在ACD。面霜(20%),染发剂(14%)和肥皂(12%)最常见。鉴定出的最常见的过敏原是没食子酸酯混合物(40%),西曲美肽(28%)和硫柳汞(20%)。在总共应用的2531个贴剂中,阳性反应率为3.75%。结论。女性中ACD化妆品的发病率更高。面霜和染发剂是最常见的化妆品。主要的过敏原是没食子酸酯混合物,西曲美肽和硫柳汞。

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