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DPP-4 inhibitor sitagliptin prevents inflammation and oxidative stress of heart and kidney in two kidney and one clip (2K1C) rats

机译：DPP-4抑制剂西他列汀可预防两只肾脏和一只夹子（2K1C）大鼠的炎症和心脏和肾脏的氧化应激

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BackgroundHyperglycemia and insulin resistance often develop cardiovascular and nephrological dysfunction in diabetic patients. Sitagliptin is used to treat diabetes and showed potential benefit in lowering increased blood glucose level in diabetes. This investigation reports the effect of sitagliptin treatment on oxidative stress in kidney and heart of 2K1C rats.

机译：背景高血糖和胰岛素抵抗通常在糖尿病患者中发展为心血管和肾病功能障碍。西他列汀用于治疗糖尿病，并显示出降低糖尿病中升高的血糖水平的潜在益处。这项研究报告了西他列汀治疗对2K1C大鼠肾脏和心脏氧化应激的影响。

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期刊名称 Diabetology Metabolic Syndrome
作者
Md. Ashraful Alam; Mohammed Riaz Hasan Chowdhury; Preeti Jain; Md. Abu Taher Sagor; Hasan Mahmud Reza;
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作者单位

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年(卷),期 2015(7),-1
年度 2015
页码 107
总页数 10
原文格式 PDF
正文语种
中图分类基础医学;
关键词
Sitagliptin Fibrosis Inflammation Oxidative stress Malondialdehyde;

机译：西他列汀;纤维化;炎症;氧化应激;丙二醛;

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专利

1. Polyphenolic compounds of amla prevent oxidative stress and fibrosis in the kidney and heart of 2K1C rats [J] . Md. Mizanur Rahman, Khandoker Usran Ferdous, Shraboni Roy, Food Science & Nutrition . 2020,第7期

机译：AMLA的多酚类化合物防止肾脏和2K1C大鼠心脏氧化应激和纤维化
2. Spin-Labelled 1-Ethyl-1-Nitrosourea Prevents Doxorubicin and Bleomycin-Induced Oxidative Stress in Lungs, Hearts and Kidneys of Tumour-Bearing Mice [J] . Veselina G. Gadjeva, Galina D. Nikolova, Boncho G. Grigorov, Advances in Biological Chemistry . 2014,第5期

机译：自旋束缚的1-乙基-1-硝基硫脲预防阿霉素和博来霉素诱导的荷瘤小鼠肺，心脏和肾脏的氧化应激
3. Phyllanthus niruri leaves aqueous extract improves kidney functions, ameliorates kidney oxidative stress, inflammation, fibrosis and apoptosis and enhances kidney cell proliferation in adult male rats with diabetes mellitus [J] . Giribabu Nelli, Karim Kamarulzaman, Kilari Eswar Kumar, Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs . 2017,第期

机译：Phyllanthus niruri叶水提取物改善肾功能，改善肾氧化应激，炎症，纤维化和凋亡，增强成年男性大鼠的肾细胞增殖与糖尿病
4. Effect of resveratrol on oxidative stress in kidneys of diabetic rats [C] . Lu-jia Zhu, Li-jing Zhang 2011 International Conference on Human Health and Biomedical Engineering . 2011

机译：白藜芦醇对糖尿病大鼠肾脏氧化应激的影响
5. Registration and segmentation in perfusion MRI: Kidneys and hearts. [D] . Sun, Ying. 2004

机译：灌注MRI中的配准和分割：肾脏和心脏。
6. Polyphenolic compounds of amla prevent oxidative stress and fibrosis in the kidney and heart of 2K1C rats [O] . Md. Mizanur Rahman, Khandoker Usran Ferdous, Shraboni Roy, 2020

机译：Amla多酚化合物可预防2K1C大鼠肾脏和心脏的氧化应激和纤维化
7. DPP-4 inhibitor sitagliptin prevents inflammation and oxidative stress of heart and kidney in two kidney and one clip (2K1C) rats [O] . 2015

机译：DPP-4抑制剂西他列汀可预防两只肾脏和一只夹子（2K1C）大鼠的心脏和肾脏发炎和氧化应激

DPP-4 inhibitor sitagliptin prevents inflammation and oxidative stress of heart and kidney in two kidney and one clip (2K1C) rats

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