The total alkaloids from Coptis chinensis Franch improve cognitive deficits in type 2 diabetic rats

机译：黄连总生物碱可改善2型糖尿病大鼠的认知功能障碍

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摘要

BackgroundCoptis chinensis Franch is extensively used in traditional Chinese medicine to treat diabetes and dementia. Alkaloids are the main active ingredients of C. chinensis.

机译：背景黄连在传统中药中广泛用于治疗糖尿病和痴呆症。生物碱是C. chinensis的主要活性成分。

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期刊名称 Drug Design Development and Therapy
作者
Jia-Chuan Li; Xiao-Fei Shen; Jun-Ao Shao; Meng-Min Tao; Jian Gu; Jingyu Li; Ning Huang;
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作者单位

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年(卷),期 2018(12),-1
年度 2018
页码 2695–2706
总页数 12
原文格式 PDF
正文语种
中图分类药学;药物化学;
关键词
cognitive deficits type 2 diabetes Coptis chinensis Franch total alkaloids insulin signaling;

机译：认知缺陷;2型糖尿病;黄连;总生物碱;胰岛素信号传导;
入库时间 2022-08-17 12:15:57

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专利

1. The total alkaloids from Coptis chinensis Franch improve cognitive deficits in type 2 diabetic rats [J] . Jia-Chuan Li, Xiao-Fei Shen, Jun-Ao Shao, Drug Design, Development and Therapy . 2018,第4期

机译：黄连总生物碱可改善2型糖尿病大鼠的认知功能障碍
2. Simultaneous Determination of Eight Alkaloids in Rat Plasma by UHPLC-MS/MS after Oral Administration of Coptis deltoidea C. Y. Cheng et Hsiao and Coptis chinensis Franch [J] . Liu Lu, Wang Zhi-Bin, Song Yang, Molecules . 2016,第7期

机译：口服黄连和黄连的超高效液相色谱-质谱联用同时测定大鼠血浆中的八种生物碱
3. Simultaneous Determination of Eight Alkaloids in Rat Plasma by UHPLC-MS/MS after Oral Administration of Coptis deltoidea C. Y. Cheng et Hsiao and Coptis chinensis Franch [J] . Lu Liu, Zhi-Bin Wang, Yang Song, Molecules . 2016,第7期

机译：口服黄连和黄连的超高效液相色谱-质谱联用同时测定大鼠血浆中的八种生物碱
4. Study on Distribution Behavior in Aqueous Two-phase System about Four Kinds of Alkaloids in Coptis Chinensis [C] . Fengwei Wang, Daowu Wang, Qingfeng Guo, International Conference on Materials, Environmental and Biological Engineering . 2015

机译：两组系统中三种生物碱水溶液分布行为研究COPTIS Chinensis
5. Part I: The first regio- and atropdiastereoselective total synthesis of the dimeric indole alkaloid (+)-dispegatrine, as well as the first total synthesis of the sarpagine alkaloids (+)-spegatrine, lochvinerine, (+)-lochneram and an improved total synthesis of (+)-10-methoxyvellosimine, (+)-lochnerine and (+)-sarpagine. Part II: Studies directed toward the total synthesis of the carbon-19 methyl substituted sarpagine-macroline alkaloids (+)-macro-salhine chloride as well as macrocarpine A, B and C. [D] . Edwankar, Chitra R. 2011

机译：第一部分：二聚吲哚生物碱（+）-dispegatrine的第一个区域和对映异构选择性全合成，以及sarpagine生物碱（+）-spegatrine，lochvinerine，（+）-lochneram的第一个全合成（+）-10-甲氧基玻璃素胺，（+）-氯精胺和（+）-sarpagine的合成。第二部分：研究碳19甲基取代的沙雷帕金-大麦碱生物碱（+）-大-沙丁鱼碱氯化物以及大芸香碱A，B和C的总合成。
6. Simultaneous Determination of Eight Alkaloids in Rat Plasma by UHPLC-MS/MS after Oral Administration of Coptis deltoidea C. Y. Cheng et Hsiao and Coptis chinensis Franch [O] . Lu Liu, Zhi-Bin Wang, Yang Song, 2016

机译：黄连口服和黄连口服UHPLC-MS / MS同时测定大鼠血浆中8种生物碱
7. Simultaneous Determination of Eight Alkaloids in Rat Plasma by UHPLC-MS/MS after Oral Administration of Coptis deltoidea C. Y. Cheng et Hsiao and Coptis chinensis Franch [O] . Lu Liu, Zhi-Bin Wang, Yang Song, 2016

机译：口服黄连后用UHpLC-ms / ms同时测定大鼠血浆中8种生物碱Y. Cheng et Hsiao和Coptis chinensis Franch

The total alkaloids from Coptis chinensis Franch improve cognitive deficits in type 2 diabetic rats

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