Endemic malaria: an indoor disease in northern Europe. Historical data analysed

摘要

BackgroundEndemic northern malaria reached 68°N latitude in Europe during the 19^th century, where the summer mean temperature only irregularly exceeded 16°C, the lower limit needed for sporogony of Plasmodium vivax. Because of the available historical material and little use of quinine, Finland was suitable for an analysis of endemic malaria and temperature.