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Caution is required when using health facility-based data to evaluate the health impact of malaria control efforts in Africa

机译:在使用基于卫生机构的数据评估非洲疟疾控制工作对健康的影响时需要谨慎

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摘要

The global health community is interested in the health impact of the billions of dollars invested to fight malaria in Africa. A recent publication used trends in malaria cases and deaths based on health facility records to evaluate the impact of malaria control efforts in Rwanda and Ethiopia. Although the authors demonstrate the use of facility-based data to estimate the impact of malaria control efforts, they also illustrate several pitfalls of such analyses that should be avoided, minimized, or actively acknowledged. A critique of this analysis is presented because many country programmes and donors are interested in evaluating programmatic impact with facility-based data. Key concerns related to: 1) clarifying the objective of the analysis; 2) data validity; 3) data representativeness; 4) the exploration of trends in factors that could influence malaria rates and thus confound the relationship between intervention scale-up and the observed changes in malaria outcomes; 5) the analytic approaches, including small numbers of patient outcomes, selective reporting of results, and choice of statistical and modeling methods; and 6) internal inconsistency on the strength and interpretation of the data. In conclusion, evaluations of malaria burden reduction using facility-based data could be very helpful, but those data should be collected, analysed, and interpreted with care, transparency, and a full recognition of their limitations.
机译:全球卫生界对投入数十亿美元用于抗击非洲疟疾的健康影响感兴趣。最近的出版物使用了基于医疗机构记录的疟疾病例和死亡趋势来评估卢旺达和埃塞俄比亚疟疾控制工作的影响。尽管作者展示了使用基于设施的数据来估计疟疾控制工作的影响,但他们还说明了应避免,最小化或积极承认的此类分析的几个陷阱。之所以提出这种批评,是因为许多国家计划和捐助者都对利用基于设施的数据评估计划影响感兴趣。主要关注点涉及:1)明确分析的目的; 2)数据有效性; 3)数据代表性; 4)探索可能影响疟疾发病率的因素趋势,从而混淆干预规模扩大与观察到的疟疾结果变化之间的关系; 5)分析方法,包括少量的患者结果,选择性报告结果以及选择统计和建模方法; 6)内部在数据强度和解释上的不一致。总之,使用基于设施的数据对减少疟疾负担的评估可能非常有帮助,但应谨慎,透明并充分认识到其局限性,对这些数据进行收集,分析和解释。

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